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Safety Assessment Acute toxicity A single subcutaneous injection of AOD 9604 (50 mg/kg) did not cause death or obvious toxic reactions in mice

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Skin fibroblasts, are quite resistant and are the first to be exposed, on the other hand, neural cells are very sensitive to any external stimuli and their regenerative capacity is very low

Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea