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Pediatr Neurol, 2005

Other proposed nitrite reductases catalyzing NO formation from nitrite under hypoxic conditions are carbonic anhydrase (1), xanthine oxidase (68), or eNOS (189), which are all present in RBCs

Pauschale Empfehlungen fr langfristige Anwendungen mchte er nicht geben: Dazu fehlen noch fundierte Daten, besonders im Longevity-Kontext. Klar sei aber: Glutathion ist kein Ersatz fr einen gesunden Lebensstil

Together, these gaps underscore that OSCs should not be positioned as near-term therapeutic agents but as mechanistically rich leads requiring stabilization, standardized formulations, and biomarker-driven early-phase studies