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Although the precise mechanisms underlying IDD remain incompletely understood, The pathogenesis of the condition is influenced by a multitude of factors, as illustrated in Figure 2

International Journal of Radiation Oncology Biology Physics 114(1):78-88, 2022

Furthermore, elevated levels of ROS have been associated with a decrease in meiotic completion 34, 35 and age-associated phenotypes including altered spindle microtubules, chromosome misalignment 36,37,38 , aneuploidy 15, 39 and diminishing embryo developmental potential 32, 40,41,42,43,44

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