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The Reed model provides a comprehensive mathematical representation of one-carbon GSH metabolism, boasting the inclusion of the transsulfuration pathway, as well as glutathione synthesis, transport and breakdown

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rxlist.com (Phospholine ) Keywords Sarin (GB) Drug Class: Organophosphate anticholinesterase & a human-made chemical warfare agent (nerve agent) Originally synthesized as a pesticide Mechanism of Action: Inhibitor of different cholinesterase enzymes, including acetylcholinesterase, which is expressed by tissues that also express nicotinic or muscarinic receptors

Among the 50 genes within the overlap, Cd14 , Tifa , and Saa3 are most strongly upregulated at the RNA level, with Cd14 being mainly expressed by macrophages and interacting with LPS, while Tifa contributes to the activation of NFB and MAPK signaling during inflammation ( Figure 5C )