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This allows researchers to test a range of doses on a smaller cohort, identifying the minimum effective dose and any potential adverse effects before committing to a larger, more resource-intensive study

1 2 "Glutamine and glutamate: Nonessential or essential amino acids?"

Yeo BTT, Krienen FM, Sepulcre J, Sabuncu MR, Lashkari D, Hollinshead M, et al

In detail, a -conjugated chromophore with strong intramolecular charge transfer ability was formed by thiophene, triphenylamine, and pyridinium groups, and then linked two chromophores with one flexible octyl group to construct the dimeric photosensitizer D1 (Figure 10B) (Tang et al., 2023)