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"Vitamin B12 Deficiency and the Nervous System: Beyond Metabolic DecompensationComparing Biological Models and Gaining New Insights into Molecular and Cellular Mechanisms"

To date, vitamin B12 is officially included as supplement to pemetrexed treatment (a chemotherapeutic used in pleural mesothelioma and non-small cell lung cancer because of its folate similarity and inhibition of purine and pyrimidine synthesis)

[DOI] [PubMed] [Google Scholar] 78

In addition to encouraging apoptosis, miR-6881-3p also influences GCs by modifying the expression of gonadotropin receptors (follicle-stimulating hormone receptor, or FSHR), luteinizing hormone/choriogonadotropin receptor, or LHCGR, and enzymes that produce steroid hormones, like cholesterol side-chain lyase (cytochrome P450 family 11 subfamily A member 1, or CYP11A1)