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Figure 3 A comparison of the pattern of intracellular carnitine and its derivatives in PBMC and erylysate, as well as between both groups, revealed notable differences

Briefly, l-norcarnitine (3-hydroxy-4-dimethylaminobutyric acid) was prepared from l-carnitine (Chem Impex International) with thiophenol (Sigma-Aldrich) in N , N -dimethylaminoethanol (Sigma-Aldrich) and then was converted to its sodium salt with sodium hydroxide by the method of Colucci et al

The activation of the FOXO family, which may be due to TNF-, soluble TNF-like weak inducer of apoptosis (TWEAK), or IL-1, is common in skeletal muscle atrophy [15, 16]