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The rationale for butyrate enemas in radiation proctitis is the same as for diversion colitis: radiation destroys the mucosal microenvironment, depletes butyrate-producing bacteria, impairs colonocyte energy metabolism, and compromises the barrier

Balancing of terminal crtZ , crtW and crtZW expression results in biosynthesis of astaxanthin as major carotenoid The two identified pathway engineering strategies, namely an improved precursor supply and an optimized terminal fusion protein, were combined in strain BETA6 (pSH1-crtZ ~ m ~ W) (Fig

AGEs, recognized as uremic toxins in DN, are implicated in various pathways contributing to cellular senescence

2016 Nov;101(11):3879-3883