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In addition, enhanced NO signaling via glyceraldehyde -3- phosphate dehydrogenase (GAPDH) in the brains of AD patients shifts the balance toward tau acetylation, and inhibition of GAPDH-mediated NO signaling can help alleviate A induced cognitive deficits (Sen et al., 2018)

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Oral administration of a humid extract of dehydrated leaves is used to treat menorrhagia and diabetes in Australia, and oral administration of an extract of root bark is used to treat fever (9, 88)