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Since the conformation of chloride ion channels is regulated by ATP levels, these channels are affected by the oxidative stress caused by pyocyanin which is over-produced by most P

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De Groot ANJA, Vree TB, Hekster YA et al (1994) Pharmacokinetics and bioavailability of oral ergometrine in male volunteers

In the connection to inflammation, we showed that elevation of pro-inflammatory cytokine IL-6, increased anxiety at the lightdark test, and smaller hippocampal volume characterized at baseline (before any applied stress) those mice that become susceptible after social defeat stress (SDS) with social withdrawal and impaired transcriptomic-wide changes in ventral dentate gyrus, and that administration of LAC promoted behavioral resilience at the SDS paradigm in this susceptible phenotype [27]