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In this study, sixty-one patients with advanced solid tumors were given daily or a weekly dose of TAK-228 alone or in combination with paclitaxcel

Extracellular vesicles, also known as exosomes (EXOs), have been increasingly recognized as a promising tool for mitigating tendon aging, with potential applications in tissue regeneration and repair (9), and the purified exosomes can also improve the biomechanics of the rotator cuff (149)