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96 The iron from lysosomes appears to be taken up into mitochondria, contributing alongside ROS to the opening of the MPTP and subsequent cell death

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

Plexins may promote the growth of androgen-independent prostate cancer through their activity as RanGAPs

Review: soluble innate immune pattern-recognition proteins for clearing dying cells and cellular components: implications on exacerbating or resolving inflammation