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For the final stage of maturation into functional hepatocyte-like cells (HLCs), the proliferative HBs were cultured in hepatoZYME-SFM medium supplemented with 1X GlutaMAX

Clinical trials for both mazdutide and retatrutide have not shown elevated rates of pancreatitis, but the sample sizes and durations are still relatively small compared to the decades of post-market surveillance available for older medications