glutathione-dependent formaldehyde oxidation pathway The failure of two major catabolism enzymes (ADH5 and ALDH2) leads to partial synthetic lethality in C57BL/6 mice | Genes and Environment Deciphering Functions of Intracellular Formaldehyde:
Deciphering Functions of Intracellular Formaldehyde: Linking Cancer and Aldehyde Metabolism Biochemistry Formaldehyde metabolism and formaldehydeinduced stimulation of lactate production and glutathione export in cultured neurons Tulpule 2013 Journal of Neurochemistry Wiley Online Library Microbial Formaldehyde Oxidation UNT Digital Library Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity Nature Communications
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