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The GIP-induced peripheral promotion of positive energy balance is likely to be far less effective than the GLP- 1/GIP dual agonist's direct action on the central nervous system, which results in satiety and weight loss

In the form of 5-deoxyadenosylcobalamin, it serves as a cofactor for the enzyme methylmalonyl CoA mutase (EC 5.4.99.2), which catalyzes the mitochondrial conversion of methylmalonyl CoA to succinyl CoA as an intermediate step in the oxidation of odd-chain FAs and the catabolism of ketogenic amino acids