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The findings that loss of claudin-7 expression induces sloughing of intestinal epithelial cells (claudin-7 KO mice), possibly by disrupting the complex between claudin-1, claudin-7 and 1-integrin, highlights the previously underappreciated roles of TJ proteins in cellmatrix interactions

pylori infections exhibit higher amounts of ROS and NO-derived metabolites, which show that iNOS has been activated (37)

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That said, supplements are exactly what their name suggests: they supplement your diet