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This amplifies the ATF4/CHOP/ChaC1 cascade under ER stress, resulting in decreased intracellular GSH and cysteine, increased intracellular ROS, redox homeostasis disruption, secondary oxidative stress in cancer cells and selective ferroptosis of cancer cells (66,100)

More recently, clinical laboratories are using high throughput automated competitive binding chemiluminescence assays (CBLA), using purified intrinsic factor as a reagent to measure total vitamin B12 after its release from endogenous binding proteins

Antioxidant potential and content of the polyphenolic secondary metabolites of white rot macrofungi

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