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Description

Numerous mechanisms have been proposed to explain how EcN promotes the resolution of gastrointestinal disorders, ranging from restriction of pathogenic strains via nutritional competition or the secretion of antimicrobial compounds, to immunomodulatory effects, to strengthening of the intestinal epithelial barrier 6,9,10,11,12

387 Early clinical trials subsequently evaluated modified vaccinia Ankara (MVA), which encodes wild-type p53, in patients with resistant epithelial ovarian cancer and refractory gastrointestinal malignancies