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Low doses of 3-aminobenzamide, a poly(ADP-ribose) polymerase inhibitor, stimulate angiogenesis by regulating expression of urokinase type plasminogen activator and matrix metalloprotease 2

It was found that miR-21 is a pro-fibrotic factor that is highly expressed in response to radiation stimulation, and that high levels of miR-21 promote the expression of extracellular matrix regulatory genes GDF15, Grem1 and CCL7 [248]