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Each polypeptide folds into a left-handed helix that repeats every third residue with the side chains on the outside

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Show details PMCPubMed Central citations PubChem BioAssay for Chemical ProbePubChem BioAssay records reporting screening data for the development of the chemical probe(s) described in this book chapter PubChem SubstanceRelated PubChem Substances PubMedLinks to PubMed Inhibition of D-2HG leads to upregulation of a proinflammatory gene signature in a novel HLA-A2/HLA-DR1 transgenic mouse model of IDH1R132H-expressing glioma.[J Immunother Cancer

Apigenin suppresses cancer progression via classical modalities Apigenin has been found to influence multiple phases of the cell cycle in a variety of cancers, including skin, liver, breast, and colon cancers, primarily by causing G0/G1 phase arrest, blocking the transition from G0/G1 to S phase, and disrupting progression through the G2/M phase, thereby inhibiting cell proliferation [76]