glutathione peroxidase 1 contain heme Frontiers The glutathione peroxidase family: Discoveries

ISBN: 978-0-323-08691-2 Kowalkowski K, Klapczynski M, Blomme E, Buck W, Liguori M (2017) Evaluating in vitro canine kidney slices as a renal toxicity model using nephrotoxic agents cisplatin and cadmium chloride

Front Neurosci 12:214 Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ, Herbach N, Aichler M, Walch A, Eggenhofer E, Basavarajappa D, Radmark O, Kobayashi S, Seibt T, Beck H, Neff F, Esposito I, Wanke R, Forster H, Yefremova O, Heinrichmeyer M, Bornkamm GW, Geissler EK, Thomas SB, Stockwell BR, O'Donnell VB, Kagan VE, Schick JA, Conrad M (2014) Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

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Since STS is an inexpensive compound with low toxicity and proven safety track record of clinical use as an antidote for cyanide intoxication, STS is one of the most clinically relevant H 2 S- or reactive sulfur species-related compounds