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Apart from -synuclein, Lewy bodies also contain many other aggregated cellular proteins, which together constitute an interactome to promote fibrillation of -synuclein (Lashuel and Novello, 2021)

Lastly, activated microglia release proinflammatory cytokines like TNF-alpha and IL-1beta, inducing leukocyte infiltration, edema, and neurotoxicity (Jarrahi et al., 2020)

[ CrossRef ] [ PubMed ] Xu H, Jia C, Cheng W, Zhang T, Tao R, Ma Y, Li J The effect of L-carnitine additive during in vitro maturation on the vitrification of pig oocytes

Zhong Nan Da Xue Xue Bao Yi Xue Ban 45(2):115122 Shi XD, Li GC, Qian ZX, Jin ZQ, Song Y (2008) Randomized and controlled clinical study of modified prescriptions of Simiao pill in the treatment of acute gouty arthritis