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If the patient cannot find an understanding or knowledgeable doctor, unfortunately, the burden will be on the patient, regardless of their current mental and physical state, to find a doctor willing to be educated about the problem

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53 Future Directions Migraine and mood disorders are highly comorbid conditions, both of which appear responsive to ketamine treatment, which raises the need for more research into the role of the glutamatergic pathway in migraine pathophysiology, as has been done for major depressive disorder and stress processing