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However, the PDMS block was fabricated to minimize its footprint, implants were retrieved cleanly after animal sacrifice, and measurements were made in regions where the epineurium appeared intact (even if thickened), suggesting that such impacts were unlikely to be substantial

The drug reduces the production of inflammatory cytokines, such as TNF-alpha and IL-6, and lowers oxidative stress an imbalance between reactive oxygen species and antioxidants, the substances that eliminate them by reducing the production of reactive oxygen species