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Venkateshappa et al., 2012)

Expression of the kynurenine pathway enzyme tryptophan 2,3-dioxygenase is increased in the frontal cortex of individuals with schizophrenia

If they cannot, that is a significant red flag

For this, we combine two molecular modules: a rice NADPH-dependent thioredoxin reductase C (NTRC) and roGFP2 as NADPH sensing and output components, respectively