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Additionally, depressed mice exhibited decreased levels of lactobacilli in the gut tract, while supplementation of probiotics significantly increased the abundance of lactobacilli and improved anxiety and depression-like symptoms induced by chronic mild stress in mice [191]

Supervised machine learning can aid in the unbiased selection of novel PA biomarkers We noted the small number of participants in some classes identified by unsupervised machine learning (e.g., only two participants in cluster 3 as in Fig