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Preclinical Studies Early preclinical studies in rodent obesity models demonstrated that AOD9604 administration reduced body weight and fat mass without affecting food intake, indicating a direct metabolic effect rather than an appetite-suppressing mechanism

Finally, the beads were washed twice with 75 mM NaCl in 50 mM Tris-HCl (pH 8.0), frozen in 50 l of the buffer and stored until further processing

(2000) which estimates $r$ dependent on sex, height and weight: $$r_{\text{female = 0 + 0 $$ $$r_{\text{male = 0 + 0 $$ These linear equations can give really strange values for $r$, for example, if you weight a lot