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Cellular thermal shift assay (CETSA) For intact-cell CETSA experiments, cells were pretreated with 10 M compound or DMSO control (0.1%, v/v) for 1 h at 37 C

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Procedures like laser therapy and chemical peels not only lighten the skin but also stimulate collagen production, which helps to reduce fine lines and wrinkles, and this dual action makes the skin look younger and more vibrant