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However, the downregulation of p53 cannot prevent cell cycle arrest or the induction of senescence after the overexpression of p16

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Considering that this amino acid is essential for central nervous system (CNS) function and development (46), its decline has been associated with severe neurological disorders (47, 48)

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The two were then combined and incubated for 20 min before added into 20 mL of cells at a density of 2 10 6 cells per mL

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