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The first signs of dracunculiasis occur around a year after infection, as the full-grown female worm prepares to leave the infected persons body

10.1016/s0021-9258(19)88673-8 80 NakaD.ShimomuraT.YoshiyamaY.SatoM.SatoM.IshiiT.et al (1993)

Archives of Gerontology and Geriatrics , 44 (Suppl 1), 213216

Both mechanisms act on vascular smooth muscle, precapillary sphincters, and pericytes, with particularly strong effects at the level of precapillaries and capillaries, highlighting the key role of these microvascular segments in CVR ( Astrocytes also contribute to CVR through CO 2 -dependent intracellular Ca 2+ signaling