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Poor nutritional status is often associated with chronic alcoholism, and thus alcoholic patients with APAP-induced hepatotoxicity may fall victim to both decreased body GSH stores as well as enhancement of the CYP enzymatic activity

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Disclosures: Liang Wen: Nothing to Disclose, Yixiao Yang: Nothing to Disclose, Tingbo Liang: Nothing to Disclose 2639 PREDICTING SURVIVAL AMONG PATIENTS WITH EARLY- TO INTERMEDIATE-STAGE HCC: MIAMI LIVER CANCER ESTIMATOR OF SURVIVAL (MILES) SCORE David Goldberg 1 David Kaplan 2 Binu John 1 Neelima Gaddipati 1 Sirisha Gaddipati 1 Yalda Zarnegarnia 1 Peter Reese 2 Catherine Blandon 1 , 1 University of Miami, 2 University of Pennsylvania Background: Staging and prognostication of hepatocellular carcinoma (HCC) differs from other cancers because it must account for tumor burden as well as function of the diseased organ (i.e., liver)