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These results are confirmed by those from other studies in HPV-16 E7-transfected HaCaT cells [31] or HPV-16-infected keratinocytes, where viral oncoproteins expression is associated with increased resistance to UV radiation [32]

Functional analyses in the aforementioned research confirmed that CREB1 and BDNF are direct targets of miR-124, indicating that their silencing can exert antidepressant effects by restoring neuronal plasticity pathways