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Intracellular ROS, measured as fluorescence by 2,7-dichlorodifluorescein diacetate (DCFDA), was associated with exposure to aspartame at 0.1 mM (100 M), a non-cytotoxic concentration

Using bioinformatic methods, Zhou et al

Over 24 hours at room temperature, NAD + showed tendency to increase by approximately 25% and NADH by 125% from the baseline at collection, while NADP + remained stable and NADPH levels decreased 69% (Supplementary Figure 1a-f)