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Hence, an overabundance of ROS gives rise to a disturbance in the physiological endothelial function, resulting in vasoplegia, an excessive procoagulant state induced by the inhibition of the ADAMTS-13 (a disintegrin and metalloproteinase with thrombospondin motifs 13) enzyme, and impairment of mitochondrial integrity, thereby disturbing the signaling cascades governing thrombosis and inflammation (Dolmatova et al., 2021)

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Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy

A single-peptide BPC-157 cycle starts at 45