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Whole wounds of 6 mm in diameter were created within an ischaemic bicuspid flap on the back of each rat

Acknowledgments The authors thank Trudy Mcgarry, PhD (Novartis, Dublin, Ireland) and Shilpa Kakkar, PhD (Novartis Healthcare, Hyderabad, India) for providing medical writing support which was funded by Novartis Pharma AG in accordance with the Good Publication Practice (GPP3) guidelines ( The authors would also like to thank the patient advocacy groups that participated in this study: APIAFCO (Associazione Psoriasici Italiani Amici della Fondazione Corazza), Canadian Association of Psoriasis Patients, France Psoriasis, GIPSO (Groupe dAide lInformation et la Recherche sur le Psoriasis), Interregional Charitable Public Organization Skin and Allergic Diseases, Irish Skin Foundation, Japan Psoriasis Association, National Psoriasis Foundation, Psoriasis Association Korea, Psoriasis Association of Slovenia, Psoriasis Australia, Psoriasis-Contact, Psoriasis Liga Vlaanderen, Psoriasis og Eksemforbundet, Psoriasisforeningen, and Psoriasis Association Taiwan

Opioid withdrawal occurs when someone dependent or addicted to opioids suddenly or gradually stops using them

In the subsequent sections, evidence is presented supporting this hypothesis