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The potential problem is that the hype around these compounds has moved faster than the evidence

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Naunyn Schmiedebergs Arch Pharmacol 383(2):149158 Serafim C, Araruna ME, Jnior EA, Diniz M, Hiruma-Lima C, Batista L (2020) A review of the role of flavonoids in peptic ulcer (20102020)

Practical Considerations for Use Start Low, Adjust Gradually Begin with lower doses and increase based on research outcomes