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When we don't get enough vitamin B12, it can: Reduce ATP production, potentially contributing to mitochondrial dysfunction and insulin resistance Cause megaloblastic anemia, characterized by abnormally large, hemoglobin-poor red blood cells that die prematurely

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Without adequate B12, these processes begin to function sub-optimally and the effects, while not always dramatic in the early stages, accumulate in ways that many people experience as persistent tiredness, reduced mental sharpness, lower mood and a general lack of the vitality they feel they should have

(Eric Gay/AP Photo) AP People are rescued from a hotel by boat after Hurricane Harvey caused heavy flooding in Houston, Texas on August 27, 2017