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Int Urogynecol J

10.1016/j.cmet.2010.09.004 140 TilgH.ZmoraN.AdolphT

E.MartinS

Carcinogenesis of HPV through induction of ROS Mitochondrial dysfunction HPV can lead to carcinogenesis by disrupting mitochondria, a cellular powerhouse responsible for metabolism, cell growth, cell survival, apoptosis, and generating superoxide anions as byproducts during their oxidative phosphorylation (OXPHOS) in energy production process [40,41,42]