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Description

It targets tumor cells and inhibits tumor progression by reducing the production of 2-hydroxyglutarate (2-HG) mediated by isocitrate dehydrogenase 1 (IDH1mt) (84)

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Turrens JF, Boveris A: Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

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Farshi S, Mansouri P, Kasraee B

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OPZELURA may cause serious side effects, including: Serious Infections: OPZELURA contains ruxolitinib

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