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Non-motor symptoms: the hidden burden Gastrointestinal dysfunction and the gut-brain axis PD may originate in the gut before manifesting in the central nervous system (CNS) through the formation of alpha-synuclein aggregates within the visceral nervous system

Although treatment is being restricted to the groups above (e.g., rituximab patients), others will most likely be able to get it once production increases

Notably, high doses of Vitamin B (folic acid 0.8 mg, Vitamin B6 20 mg, Vitamin B12 0.5 mg) for 2 years was shown to slow the progression of brain atrophy significantly (Donnelly et al., 2008)

The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and NFB signalling pathways in monocytes/macrophages