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Through its potent antioxidant, anti-inflammatory, and hepatoprotective properties, silymarin has shown efficacy in improving liver function, reducing oxidative stress, and mitigating liver inflammation

The administration of SILY with SERT was also associated with a reversal of weight loss due to DEX-induced depressive symptoms, suggesting that compared to SERT, SILY could be beneficial in modulating the effects of SERT on body weight

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In cases of long-term excessive iron accumulation, the risk of cirrhosis and hepatocellular carcinoma increases, especially in individuals with a genetic predisposition