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Additionally, integrating biomarkerguided patient stratification (e.g., based on mitochondrial function or NTFs receptor status) into trial design may help identify subgroups most likely to benefit from axistargeted therapies

and in older individuals, hypothyroidism accelerates cognitive decline while hyperthyroidism increases anxiety and sleep disturbances ( The thyroidbrain axis represents a complex system of bidirectional communication between endocrine and neural networks

Epitalon Side Effects and Safety Profile Epitalon is generally discussed as a well-tolerated peptide in wellness and research contexts, but side effects can still occur

Jackson (2013)