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Similarly, another clinical trial tested the effect of Glutathione on skin color and other related skin conditions, and the study showed positive results on the potential of Glutathione in the above-stated field

2.20 Statistical analysis Statistical analysis was performed using SPSS 26.0 and R 4.2.1

Pro-inflammatory factors like TNF- and IL-1 upregulate inflammation-related genes through NF-B pathway activation (280)

Furthermore, compared to directly targeting LDHA, metabolic interventions aimed at upstream glycolytic regulators may elicit broader biological effects and potential unpredictability ( The aforementioned upstream intervention strategies targeting lactate production and transport offer the advantage of simultaneously reversing microenvironmental acidification and inhibiting lactylation modifications, thereby achieving dual antitumor effects