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Nature , 234 , 466467

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Combined Ibrutinib and Venetoclax in Patients with Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)

Since the payment methodology for the new add-on code for Opvee (G0532), the weekly bundled payment for weekly Brixadi (G0533), and the update to the monthly bundled payment for injectable buprenorphine (HCPCS code G2069) is based on comparable and existing drugs billed under the Medicare OTP benefit, and assuming an OTP may provide these new drugs to a Medicare beneficiary in lieu of the comparable and existing drugs under the Medicare OTP benefit (e.g, Opvee instead of Narcan or Kloxxado, or the weekly or monthly formulation of Brixadi instead of Sublocade), then CMS estimates the financial impacts of these new drugs would be negligible