chac1 er stress glutathione degradation (GSH) depletion by results in a more oxidizing ChaC1-based drug screenings identify a

ChaC1 based drug screenings identify a synergistic lethal effect of auranofin and proteasome inhibitors in hepatocellular carcinoma cells Cell Death Discovery Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF CRE Regulatory Element* Journal of Biological Chemistry Endoplasmic Reticulum Transport of Glutathione by Sec61 Is Regulated by Ero1 and Bip: Molecular Cell The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2: Cell Reports

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