Additionally, ROS are produced when TLR1, TLR2, and TLR4 stimulate the translocation of tumor necrosis factor receptor-associated factor 6 (TRAF6) into the mitochondria, promoting the degradation of the evolutionarily conserved signaling intermediate in the toll (ECSIT) protein (West et al., 2011)

INCI Aqua, Glycerin, PEG-8, Niacinamide, Butylene Glycol, Methylpropanediol, 1,2-Hexanediol, Methyl Gluceth-20, Glycereth-26, Bis-PEG-18 Methyl Ether Dimethyl Silane, Betaine, Carbomer, Diphenyl Dimethicone, Tromethamine, Triethylhexanoin, Ethylhexylglycerin, C12-14 Alketh-12, Parfum, Glutathione, Xanthan Gum, Hydrogenated Lecithin, Adenosine, Coptis Japonica Extract, Polyglyceryl-10 Oleate, Disodium EDTA, Collagen, Polyglyceryl-10 Laurate, Saccharide Hydrolysate, Panthenol, Theobroma Cacao Seed Extract, Dextrin, Sodium Hyaluronate, Stellaria Media Extract, Sorbitan Laurate, Prunella Vulgaris Extract, Lactobacillus Ferment, Fucus Vesiculosus Extract, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Equisetum Arvense Extract, Caprylyl Glycol, Lycopodium Clavatum Extract, Hyaluronic Acid, Palmitoyl Tripeptide-5, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Acetyl Octapeptide-3, Sodium Acetylated Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Hydrolyzed Keratin, Hydrolyzed Collagen, Hydrolyzed Silk

This approach challenges more traditional road safety strategies where some degree of death and injury is seen as an acceptable price to pay for the benefit of car-based mobility
Clinical Journal of Peptide Therapy, 28 (2), 78-88