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Journal of Investigative Dermatology, 143(4), 10201030.e5

Zhang X, Zhang H, Gu J, Zhang J, Shi H, Qian H, Wang D, Xu W, Pan J, Santos HA

concluded that it is safe, well-tolerated, alternative treatment for AN when an etiological treatment is not possible or necessary

Future studies are still needed to further clarify the causal relationships of amino acid metabolism in autoimmune diseases and its hierarchical position in immune regulation through more systematic genetic studies, metabolic flux analyses, and single-cell multi-omics approaches, so as to distinguish its specific role as a disease driver or as a passenger/metabolic marker