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Apc Min /+ mice have a mutation in the Apc (adenomatous polyposis coli) gene similar to that in humans with familial adenomatous polyposis, a genetic condition characterized by the development of numerous colorectal adenomas (polyps) and a high risk for colorectal cancer

Role played by reduced glutathione, and quantitative assay of the feeding reflex

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We feel there may be a relationship between HCCAA and other cerebral amyloid angiopathies like Alzheimers disease that is analogous to that of familial combined hypercholesterolemia (FCH) and general hypercholesterolemia