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Cell 187 , 55305539 (2024)

Prabhus group showed that direct exposure to acrolein (as low as 0.01 M) induced myofilament dysfunction in vitro and in vivo (1 mg/kg/day intravenous) in mice (Ismahil et al

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In particular, p-glycoprotein reduces the efficacy of various antiepileptic drugs (AEDs) by transporting them from the brain to the blood and restricting their access to the brain (162)