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Cell 14 (1), 7685 (2008)

Afonso AC, Oliveira D, Saavedra MJ, et al (2021) Biofilms in diabetic foot ulcers: impact, risk factors and control strategies

This underdiagnosis can lead, besides death in 20% when it is not appropriately treated, to Korsakoffs syndrome, a severe dysfunction often following untreated Wernickes encephalopathy, that does not remit even with thiamine treatment and is associated with chronic alcohol abuse and chronic thiamine deficiency (40, 42)

Randomized controlled trials in RLS patients have shown ferrous sulfate , at 325 mg (providing 65 mg elemental iron) twice daily, improved symptoms (Wang 2009